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What are the major causes of cirrhosis?

Cirrhosis can be caused by a number of conditions, such as

  • Chronic alcoholism / Excessive use of alcohol
  • Viral infections caused by chronic viral hepatitis (types A, B and C)
  • Highly toxin condition of the body system
  • Poor nutrition
  • Metabolic diseases such as alpha-1-antitrypsin deficiency, galactosemia and glycogen storage disorders
  • Inherited diseases such as Wilson's disease and hemochromatosis
  • Biliary cirrhosis resulting from diseases such as primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC)
  • Toxic hepatitis caused by severe reactions to prescribed drugs or prolonged exposure to environmental toxins
  • Repeated bouts of heart failure with liver congestion.

The main damage in cirrhosis is triggered by scarring (fibrosis) that occurs from injuries due to alcohol, viruses or other assaults. Normal clumps and form nodules around the scarred areas. The scar tissue and regenerated nodules act like small dams and alter the flow of blood and bile in and out of the liver. Liver Fibrosis is the first stage of liver scarring. Later, if more of the liver becomes scarred, it's known as liver cirrhosis. Consulting our doctor at an early stage of liver disease.

This picture displays a Liver with Hepatic Cirrhosis, Macronudular type.

Causes of Liver cirrhosis